Sinocal D
Description
đ Sinocal D â Calcium Carbonate 500 mg
Manufacturer: SinoHealth Pharmaceuticals LTD
1. Presentation:
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Tablet: 500 mg Calcium Carbonate (equivalent to Elemental Calcium 200 mg approx.)
2. Description / Pharmacology:
Calcium carbonate is a calcium supplement and antacid that helps maintain calcium balance in the body.
It reacts with gastric acid to form calcium chloride, water, and carbon dioxide, thereby neutralizing excess stomach acid:
CaCOâ + 2HCl â CaClâ + HâO + COâ
This reaction increases gastric pH and reduces pepsin activity, providing relief from acidity.
Up to 30% of the oral dose of calcium carbonate is absorbed from the intestine.
3. Indications:
Sinocal D 500 mg is indicated for the treatment or prevention of calcium deficiency in patients with inadequate dietary calcium intake.
It is useful in:
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Hypoparathyroidism
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Vitamin D deficiency
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Chronic diarrhea or steatorrhea
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Pregnancy & lactation
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Postmenopausal women
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Renal failure or dialysis patients (as phosphate binder)
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Prevention of osteoporosis
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4. Dosage & Administration:
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Adults: 1â2 tablets (500â1000 mg) daily or as directed by a physician
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Children: Half of adult dose
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Pregnancy & lactation: 1â1.5 g calcium daily (as recommended by physician)
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Chronic renal failure: 2.5â9.0 g Calcium Carbonate daily, adjusted per serum phosphate level
đĄ Tablets should be taken with meals to enhance absorption and phosphate binding.
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5. Drug Interactions:
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May enhance cardiac glycoside (e.g., digoxin) effects if hypercalcemia develops.
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May reduce absorption of tetracycline antibiotics.
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In renal failure, vitamin D dose may require adjustment.
6. Contraindications:
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Hypercalcemia
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Hyperparathyroidism
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Hypercalciuria or nephrolithiasis
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ZollingerâEllison syndrome
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Concomitant digoxin therapy (requires monitoring)
â ī¸ Use cautiously in renal or cardiac disease, or sarcoidosis.
7. Side Effects:
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Mild constipation or GI irritation
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Rarely, hypercalcemia (usually in renal impairment or overdose)
8. Pregnancy & Lactation:
Safe and widely used during pregnancy and breastfeeding for calcium supplementation and acid control.
9. Precautions & Warnings:
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Monitor serum calcium in patients with renal impairment or elderly patients.
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Long-term use should be guided by physician supervision.
10. Therapeutic Class:
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Minerals in bone formation
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Specific mineral preparations
11. Storage Conditions:
Store below 30°C in a cool, dry place, protected from light and moisture.
Keep out of reach of children.




