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Sinocal DX

Calcium Carbonate + Vitamin D₃
500mg + 200 IU
SinoHealth Pharmaceuticals LTD

Description

💊 Sinocal DX – Coral Calcium 500 mg + Vitamin D₃ 200 IU

Manufacturer: SinoHealth Pharmaceuticals LTD

1. Presentation:

Each film-coated tablet contains:

  • Calcium Carbonate USP (Coral source) – 1250 mg
    (Equivalent to 500 mg of Elemental Calcium)

  • **Vitamin D₃ (Cholecalciferol USP) – 200 IU_

2. Description / Pharmacology:

Calcium is a vital mineral necessary for the maintenance of bone strength, neuromuscular activity, and cardiac function. A deficiency can lead to bone resorption and related disorders such as osteoporosis and osteomalacia.

Vitamin D₃ (Cholecalciferol) enhances calcium absorption from the gastrointestinal tract and helps maintain proper calcium-phosphorus balance in the blood. It also promotes bone mineralization and growth.

Coral Calcium, derived from marine sources, has a chemical structure similar to human bone, ensuring superior absorption and bioavailability compared to regular calcium carbonate.
The combination of Calcium and Vitamin D₃ shows synergistic benefits in maintaining bone health and reducing fracture risks.

3. Indications:

Sinocal DX is indicated for:

  • Osteoporosis & osteopenia

  • Osteomalacia & rickets

  • Tetany & hypoparathyroidism

  • Disorders of osteogenesis

  • Calcium deficiency in children

  • Pregnancy & lactation (as supplement)

  • Elderly patients with low calcium intake

  • Chronic renal failure (as phosphate binder)

  • Pancreatitis

⚠️ রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।

4. Dosage & Administration:

  • 1 tablet once or twice daily with a full glass of water or as directed by a physician.

  • Taking after meals ensures better absorption.

  • Effervescent form: Dissolve one tablet in a glass of water, stir well, and drink immediately.

⚠️ রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।

5. Drug Interactions:

  • Thiazide diuretics: Risk of hypercalcemia — monitor serum calcium.

  • Corticosteroids: Reduce calcium absorption; may need dose adjustment.

  • Tetracyclines / Bisphosphonates: Administer 2–6 hours apart.

  • Cardiac glycosides (e.g., Digoxin): May increase toxicity if calcium rises.

  • Ion-exchange resins (e.g., Cholestyramine): May reduce Vitamin D₃ absorption.

  • Foods high in oxalate/phytate (spinach, whole grains): Decrease calcium absorption — avoid taking within 2 hours of these.

6. Contraindications:

  • Hypercalcemia or hyperparathyroidism

  • Hypercalciuria or nephrolithiasis

  • Severe renal impairment

  • Hypersensitivity to any ingredient

  • Concomitant digoxin therapy (without monitoring)

7. Side Effects:

  • Mild constipation or GI irritation

  • Rare: Hypercalcemia (especially in renal impairment or overdose)

  • Nausea, vomiting, loss of appetite, drowsiness

  • Occasional allergic reactions or irregular heartbeat

8. Pregnancy & Lactation:

Safe during pregnancy and breastfeeding when used as recommended.
Total daily intake should not exceed 1500 mg calcium and 600 IU Vitamin D₃.
Avoid overdose to prevent maternal or fetal hypercalcemia.
Calcium and Vitamin D₃ both pass into breast milk.

9. Precautions & Warnings:

  • Monitor serum calcium and renal function during prolonged therapy.

  • Use with caution in elderly, renal impairment, or sarcoidosis.

  • Avoid additional Vitamin D unless prescribed.

  • Immobilized patients with osteoporosis are at higher risk of hypercalcemia.

10. Overdose Effects:

Symptoms include nausea, vomiting, constipation, muscle weakness, bone pain, confusion, and arrhythmia.
Prolonged hypercalcemia may cause renal damage or soft tissue calcification.
Treatment: Stop calcium/Vitamin D intake, rehydrate, and use loop diuretics, bisphosphonates, or corticosteroids as needed.

11. Therapeutic Class:

Specific mineral & vitamin combined preparations

12. Storage Conditions:

Store below 30°C, protected from light & moisture.
Keep out of reach of children.

13. Common Questions (FAQ):

Q1. What is Sinocal DX used for?
➡ To prevent and treat calcium and Vitamin D₃ deficiency, strengthen bones, and reduce fracture risk.

Q2. When should I take Sinocal DX?
➡ Take after meals for better absorption.

Q3. Who should avoid it?
➡ Patients with high calcium, kidney stones, or sarcoidosis.

Q4. What are the side effects?
➡ Constipation, nausea, headache, and mild drowsiness.

Q5. Is it safe in pregnancy?
➡ Yes, under medical supervision and within the recommended daily limit.

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